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Search Results for " ischemia-reperfusion injury "

20

Compounds

Cat No. Product Name Synonyms Targets
T9073 SRS16-86 Ferroptosis
SRS16-86 is a novel third-generation ferrostatin, is an inhibitor of ferroptosis.
T9765 TJ-M2010-5 MyD88
TJ-M2010-5 is a MyD88 inhibitor that binds to the TIR domain to interfere with its homodimerization and suppress MyD88 signaling. TJ-M2010-5 can be used in myocardial ischemia/reperfusion injury studies.
T22537 9-Phenanthrol TRP/TRPV Channel
9-Phenanthrol is inhibitor of the transient receptor potential melastatin 4 (TRPM) channel, a Ca2+ -activated non-selective cation channel.
TN6490 Regaloside C Others
Regaloside C is a glycerol glucoside isolated from Lilium genus with anti-inflammatory properties.
T9232 Mitochondrial fusion promoter M1 Mitochondrial Metabolism
Mitochondrial fusion promoter M1, a modulator of mitochondrial dynamics, enhances mitochondrial function and cellular respiration, and has shown efficacy in reducing brain and cardiac damage in rats suffering from cardia...
T1677 Montelukast Singular Leukotriene Receptor , Lipoxygenase , LTR
Montelukast (Singular) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver injury...
T4612 NS309 EGFR , Potassium Channel , HER
NS309 is a nonselective activator of small- and intermediate-conductance Ca2+-activated K+ (SK/KCa2 and IK/KCa3.1) channels (EC50s range from 0.12-1.2 µM for SK channels and 10-90 nM for IK channels). It can also activat...
T1677L Montelukast sodium MK0476 Leukotriene Receptor , LTR
Montelukast sodium (MK0476) is an orally available leukotriene receptor antagonist which is widely used for the prophylaxis and chronic treatment of asthma and has been linked to rare cases of clinically apparent liver i...
T3890 Verbenalin Verbenalol β-D-glucopyranoside,Verbenaloside,Verbenalol glucoside,Cornin Others
Verbenalin (Verbenaloside) induces angiogenesis via a programmed PI3K/Akt/eNOS/VEGF signaling axis.
T6986 Sivelestat ONO5046,EI546,LY544349 Others , SARS-CoV , Serine Protease
Sivelestat (ONO5046) is a potent and selective inhibitor of neutrophil elastase with IC50 of 44 nM.
T3102 NS-1619 Apoptosis , Potassium Channel
NS1619 have cardio-protective effects after ischemia-reperfusion injury.
T3649 BGP-15 BGP15,BGP-15 2HCl PARP
BGP-15 (BGP-15 2HCl) is a PARP inhibitor with protecting effect after ischemia-reperfusion injury.
T24109 GSK329 GSK 329,GSK-329 Others
GSK329 is an effective and selective inhibitor of TNNI3 Interacting Kinase (TNNI3K). GSK329 exhibits positive cardioprotective outcomes in the model of ischemia/reperfusion cardiac injury.
T61933 MK-0159 CD38
MK-0159 is an orally available, highly potent CD38 inhibitor with myocardial injury protection for the study of cardiac ischemia and reperfusion injury.
T31795 FK-330 LS-192510,FR-260330,FK330,FK 330 NOS
FK-330 (FR-260330) is a novel orally active inducible nitric oxide synthase inhibitor with potential anticancer and antitumor activity that prevents ischemia and reperfusion injury in rat liver transplantation.
TN4661 Nodosin IL Receptor , Autophagy
Nodosin has anti-inflammatory function of Nodosin via inhibition of IL-2. Nodosin perfusion provides a potential protective effect through inducing HO-1 expression to attenuate ischemia/reperfusion injury in liver transp...
T34268 Raxofelast IRFI016,IRFI-016,IRFI 016
Raxofelast (IRFI-016) is a hydrophilic, non-systemic, vitamin-like antioxidant that reduces ischemia-reperfusion injury in testis. Raxofelast is a good candidate compound for stopping oxidative stress after acute testicu...
T2S0500 Ilexsaponin A Ilexsaponin A1 Others
1. Ilexsaponin A (Ilexsaponin A1) shows protective effects on ischemia-reperfusion-induced myocardial injury through anti-apoptotic pathway.
T4S2084 3'-Methoxypuerarin 3’- Methoxy Puerarin Antioxidant
3'-Methoxypuerarin shows neuron protection activity, it can protect hippocampal neurons against ischemia/reperfusion injury by inhibiting apoptosis. 3'-Methoxypuerarin(3’- Methoxy Puerarin) has antioxidant activities, it...
T5S2178 Fargesin (+/-)-Fargesin Adrenergic Receptor
1. Fargesin ((+/-)-Fargesin) as a potential β1AR antagonist through cAMP/PKA pathway could protect against myocardial ischemia/reperfusion injury in rats. 2. Fargesin improves dyslipidemia and hyperglycemia by activating...
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TargetMol